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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T21616 | L-006235 | L 006235 | Cysteine Protease |
L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM. | |||
TJS2216 | Aurantiamide acetate | Asperglaucide | Cysteine Protease |
Aurantiamide acetate (Asperglaucide) was isolated from the fermentation broth of Aspergillus penicilloides for the first time. Aurantiamide acetate is a selective and orally active cathepsin inhibitor. Aurantiamide aceta... | |||
T27730 | KGP94 | KGP-94,KGP 94 | Cysteine Protease |
KGP94 is an inhibitor of cysteine protease Cathepsin L(CTSL). | |||
T38469 | (Rac)-Z-Phe-Phe-FMK | Cathepsin L-IN-2 | Beta Amyloid , Cysteine Protease |
(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes . | |||
T72569 | Cathepsin L/S-IN-1 | ||
Cathepsin L/S-IN-1, a dual inhibitor targeting Cathepsin L and Cathepsin S, exhibits potent and selective inhibition with IC50 values of 4.10 μM and 1.79 μM, respectively. Demonstrating significant antimetastatic and inv... | |||
T6015 | Cathepsin Inhibitor 1 | Cysteine Protease | |
Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively. | |||
T12909 | SID 26681509 | Cysteine Protease , Parasite | |
SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM). | |||
T6564 | Leupeptin Hemisulfate | Serine Protease , Cysteine Protease | |
Leupeptin hemisulfate is a protease inhibitor with cell membrane-permeable, reversible, competitive, and oral activities. Leupeptin hemisulfate inhibits the activity of Cathepsin B, Cathepsin H, and Cathepsin L, and bloc... | |||
TN1249 | 3-Epiursolic acid | Cysteine Protease , Immunology/Inflammation related | |
3-Epiursolic acid may have antiinflammatory activity, it shows inhibition on Cathepsins L (catL), the IC50 value of 6.5 μM, cathepsins L (catL) and B play an important role in tumor progression and have been considered p... | |||
T13288 | VBY-825 | Cysteine Protease | |
VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V. | |||
T37504L | Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base) | Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base) | |
Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate for cathepsins D and E but not for B, H, or L. Cathepsin D and E FRET Substrate acetate can be used in mechanistic studies on cathepsins D and E studies... | |||
T16089 | MK-0674 | Cysteine Protease | |
MK-0674 is an orally available, selective and potent cathepsin K inhibitor (IC50: 0.4 nM) that inhibits Cat B, Cat F, Cat L, and Cat S. It can be used in metabolism-related diseases. | |||
TP2056L | Acetyl-Calpastatin (184-210)(human) acetate | Acetyl-Calpastatin (184-210) (human) acetate(123714-50-1 Free base ) | Cysteine Protease |
Acetyl-Calpastatin (184-210)(human) acetate is a potent, selective and reversible calpain inhibitor with Ki values of 0.2 nM and 6 μM for µ-calpain and cathepsin L, respectively. | |||
T1850 | Balicatib | AAE581 | Cysteine Protease |
Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis. | |||
T15641 | K777 | APC-3316 | P450 , Cysteine Protease , CCR |
K777 is a potent, orally active and irreversible inhibitor of cysteine protease. K777 is a potent CYP3A4 inhibitor (IC50= 60 nM). K777 is also a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 ... | |||
T71275 | CID16725315 | ||
Thiocarbazate, also known as CID16725315, is an inhibitor of human cathepsin L. Inhibition of cathepsin L thus holds promise for therapeutic intervention for both SARS-CoV and Ebola virus infection. With respect to th... | |||
T16092 | L-873724 | Others | |
L-873724 inhibits bone resorption. L-873724 is an effective, selective, and reversible non-basic cathepsin K inhibitor (IC50s: 0.2, 178, 264, and 5239 nM for cathepsin K, cathepsin S, cathepsin L, cathepsin B, respective... | |||
T35753 | Z-Phe-Tyr(tBu)-diazomethylketone | ||
Irreversible cathepsin L inhibitor which is ca 10'000 times more effective in inactivating cathepsin L than cathepsin S. | |||
T71618 | Oxocarbazate | ||
Oxocarbazate, also known as CID23631927, is an inhibitor of human cathepsin L. In the cathepsin L inhibition assay, The oxocarbazate caused a time-dependent 17-fold drop in IC50 from 6.9 nM (no preincubation) to 0.4 nM ... | |||
T26938 | CAA0225 | CAA 0225,CAA-0225 | |
CAA0225 is a selective inhibitor of cathepsin L. CAA0225 is a probe for autophagic proteolysis. |